Article
E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner.
Scientific reports - 5 Jun 2017
Barisa M, Kramer A M, Majani Y, Moulding D, Saraiva L, Bajaj-Elliott M, Anderson J, Gustafsson K
Abstract excerpt
γδT cells provide immune-surveillance and host defense against infection and cancer. Surprisingly, functional details of γδT cell antimicrobial immunity to infection remain largely unexplored. Limited data suggests that γδT cells can phagocytose particles and act as professional antigen-presenting cells (pAPC). These potential functions, however, remain controversial. To better understand γδT cell-bacterial...
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