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Article

Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2013

McCarthy Neil E, Bashir Zora, Vossenkämper Anna, Hedin Charlotte R, Giles Edward M, Bhattacharjee Shaumick, Brown Sabrina G, Sanders Theodore J, Whelan Kevin, MacDonald Thomas T, Lindsay James O, Stagg Andrew J

Abstract excerpt

In nonhuman primates, Vγ9Vδ2(+) (Vδ2)T cells proliferate and accumulate in mucosal tissues following microbial activation. Human Vδ2T cells produce proinflammatory cytokines in response to bacterial species that colonize the gut, but the role played by Vδ2T cells in intestinal immunity is unknown...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to Lymphocyte Culture Test, Mixed

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Share to Receptors, Antigen, T-Cell, gamma-delta

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Source

Identifiers

PMID: 23904167
DOI: 10.4049/jimmunol.1202959

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23904167-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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