Article
Genetic variation in the vitamin D related pathway and breast cancer risk in women of African ancestry in the root consortium.
International journal of cancer - 1 Jan 2018
Wang Shengfeng, Huo Dezheng, Kupfer Sonia, Alleyne Dereck, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Nathanson Katherine L, Nemesure Barbara, Ambs Stefan, Olopade Olufunmilayo I, Zheng Yonglan
Abstract excerpt
The vitamin D related pathway has been evaluated in carcinogenesis but its genetic contribution remains poorly understood. We examined single-nucleotide polymorphisms (SNPs) in the vitamin D related pathway genes using data from a genome-wide association study (GWAS) of breast cancer in the African Diaspora that included 3,686 participants (1,657 cases). Pathway- and gene-level analyses were conducted using the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
