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Article

Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry.

Molecular carcinogenesis - 1 Oct 2018

Wang Shengfeng, Huo Dezheng, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Nathanson Katherine L, Nemesure Barbara, Ambs Stefan, Olopade Olufunmilayo I, Zheng Yonglan

Abstract excerpt

Gene expression changes within the Hippo pathway were found to be associated with large tumor size and metastasis in breast cancer. The combined effect of genetic variants in genes of this pathway may have a causal role in breast cancer development. We examined 7086 SNPs that were not highly correlated (r2 < 0.8) in 35 Hippo pathway genes using data from the genome-wide association study of breast cancer from...

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Identifiers

PMID: 29873413
DOI: 10.1002/mc.22845
PMCID: PMC6662580

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WWC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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