Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.

doi:10.1007/s00439-016-1707-1

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Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.

Human genetics - 1 Oct 2016

Qian Frank, Feng Ye, Zheng Yonglan, Ogundiran Temidayo O, Ojengbede Oladosu, Zheng Wei, Blot William, Ambrosone Christine B, John Esther M, Bernstein Leslie, Hu Jennifer J, Ziegler Regina G, Nyante Sarah, Bandera Elisa V, Ingles Sue A, Press Michael F, Nathanson Katherine L, Hennis Anselm, Nemesure Barbara, Ambs Stefan, Kolonel Laurence N, Olopade Olufunmilayo I, Haiman Christopher A, Huo Dezheng

Abstract excerpt

MicroRNAs (miRNA) regulate breast biology by binding to specific RNA sequences, leading to RNA degradation and inhibition of translation of their target genes. While germline genetic variations may disrupt some of these interactions between miRNAs and their targets, studies assessing the relationship between genetic variations in the miRNA network and breast cancer risk are still limited, particularly among women...

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PMID: 27380242
DOI: 10.1007/s00439-016-1707-1
PMCID: PMC5021583

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DROSHA
ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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