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Article

The clinical value of ficolin-3 gene polymorphism in rheumatic heart disease. An Egyptian adolescents study.

BMC research notes - 26 Jan 2021

Gomaa Maher H, Khidr Emad Gamil, Elshafei Ahmed, Hamza Hala S, Fattouh Aya M, El-Husseiny Ahmed A, Aglan Ahmed, Eldeib Mahmoud Gomaa

Abstract excerpt

OBJECTIVE: Ficolin-3 is one of the innate immunity molecules that was thought to play a pivotal role in Streptococcus pyogenes autoimmunity and its complications; rheumatic fever (RF) and rheumatic heart disease (RHD). We aimed to disclose if there is an association between ficolin-3 (FCN3) gene polymorphisms (rs4494157 and rs10794501) and RF with or without RHD for the first time in Egyptian adolescents....

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Identifiers

PMID: 33499929
DOI: 10.1186/s13104-021-05450-w
PMCID: PMC7836457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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