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Article

Ribosomal selection of mRNAs with degenerate initiation triplets.

Nucleic acids research - 7 Jul 2017

Chengguang He, Sabatini Paola, Brandi Letizia, Giuliodori Anna M, Pon Cynthia L, Gualerzi Claudio O

Abstract excerpt

To assess the influence of degenerate initiation triplets on mRNA recruitment by ribosomes, five mRNAs identical but for their start codon (AUG, GUG, UUG, AUU and AUA) were offered to a limiting amount of ribosomes, alone or in competition with an identical AUGmRNA bearing a mutation conferring different electrophoretic mobility to the product. Translational efficiency and competitiveness of test mRNAs toward...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28575317
DOI: 10.1093/nar/gkx472
PMCID: PMC5499595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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