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Article

The role of upstream sequences in selecting the reading frame on tmRNA.

BMC biology - 30 Jun 2008

Miller Mickey R, Healey David W, Robison Stephen G, Dewey Jonathan D, Buskirk Allen R

Abstract excerpt

BACKGROUND: tmRNA acts first as a tRNA and then as an mRNA to rescue stalled ribosomes in eubacteria. Two unanswered questions about tmRNA function remain: how does tmRNA, lacking an anticodon, bypass the decoding machinery and enter the ribosome? Secondly, how does the ribosome choose the proper codon to resume translation on tmRNA? According to the -1 triplet hypothesis, the answer to both questions lies in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18590561
DOI: 10.1186/1741-7007-6-29
PMCID: PMC2481249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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