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Article

The more from East-Asian, the better: risk prediction of colorectal cancer risk by GWAS-identified SNPs among Japanese.

Journal of cancer research and clinical oncology - 1 Dec 2017

Abe Makiko, Ito Hidemi, Oze Isao, Nomura Masatoshi, Ogawa Yoshihiro, Matsuo Keitaro

Abstract excerpt

BACKGROUND: Little is known about the difference of genetic predisposition for CRC between ethnicities; however, many genetic traits common to colorectal cancer have been identified. This study investigated whether more SNPs identified in GWAS in East Asian population could improve the risk prediction of Japanese and explored possible application of genetic risk groups as an instrument of the risk communication....

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PMID: 28849422
DOI: 10.1007/s00432-017-2505-4

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