Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Importance of Reverse Translational Research (rTR).

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2017

Sugiyama Yuichi

Abstract excerpt

When events lead to clinical problems, the mechanisms involved often remain unclear. This is true for medications and therapies, in addition to problems inherent in an underlying disease. However, the recent development of modeling and metric methods makes it possible to estimate the relationship between side effects and various factors to explain inter-individual differences, such as genetic polymorphisms,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholestasis, Intrahepatic
Share to Databases, Factual
Share to Drug Discovery

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Interactions

Share to Drug-Related Side Effects and Adverse Reactions

Share to Medical Records

Share to Polymorphism, Single Nucleotide

Share to Translational Research, Biomedical

Source

Identifiers

PMID: 28566572
DOI: 10.1248/yakushi.16-00250-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Importance of Reverse Translational Research (rTR).PMID 28566572Read ↗

Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effectsSemantic proximity Read ↗

Research Progress of Pharmacogenomics in Drug-Induced Liver InjurySemantic proximity Read ↗

Bridging the gap between target-based and phenotypic-based drug discovery.Semantic proximity Read ↗

Multi-factorial pharmacokinetic interactions: unraveling complexities in precision drug therapySemantic proximity Read ↗

Relating drug-protein interaction network with drug side effects.Semantic proximity Read ↗

Machine Learning to Identify Interaction of Single-Nucleotide Polymorphisms as a Risk Factor for Chronic Drug-Induced Liver Injury.Semantic proximity Read ↗

Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support.Semantic proximity Read ↗

[Biomarker exploration and its clinical use].Semantic proximity Read ↗

Mechanistic Research for the Student or Educator (Part I of II)Semantic proximity Read ↗

A side effect resource to capture phenotypic effects of drugs.Semantic proximity Read ↗

Systems pharmacology modeling: an approach to improving drug safety.Semantic proximity Read ↗

Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.