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Article

Relating drug-protein interaction network with drug side effects.

Bioinformatics (Oxford, England) - 15 Sept 2012

Mizutani Sayaka, Pauwels Edouard, Stoven Véronique, Goto Susumu, Yamanishi Yoshihiro

Abstract excerpt

MOTIVATION: Identifying the emergence and underlying mechanisms of drug side effects is a challenging task in the drug development process. This underscores the importance of system-wide approaches for linking different scales of drug actions; namely drug-protein interactions (molecular scale) and side effects (phenotypic scale) toward side effect prediction for uncharacterized drugs. RESULTS: We performed a...

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Identifiers

PMID: 22962476
DOI: 10.1093/bioinformatics/bts383
PMCID: PMC3436810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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