Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An accurate genetic assay to identify human neutrophil antigen 2 deficiency.

Transfusion medicine (Oxford, England) - 1 Feb 2023

Li Yunfang, Schuller Randy M, Wu Jianming

Abstract excerpt

OBJECTIVE: We aimed to develop accurate and user-friendly genetic assays to identify the inherited neutrophil antigen-2 (HNA-2) deficiency in humans. BACKGROUND: HNA-2 is one of the most important neutrophil antigens implicated in a number of human disorders. HNA-2 deficiency or HNA-2 null is a common phenotype observed in 3%-5% Americans. HNA-2 null individuals are at risk to produce isoantibodies (or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Homozygote
Share to Isoantigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neutrophils

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 36308061
DOI: 10.1111/tme.12936
PMCID: PMC9974537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An accurate genetic assay to identify human neutrophil antigen 2 deficiency.PMID 36308061Read ↗

Genetic mechanism of human neutrophil antigen 2 deficiency and expression variations.Semantic proximity Read ↗

A novel nonsense mutation found in the CD177 gene of Thai individuals with the HNA-2 null phenotype.Semantic proximity Read ↗

Molecular Genetics of the Human Neutrophil AntigensSemantic proximity Read ↗

Molecular studies reveal that A134T, G156A and G1333A SNPs in the CD177 gene are associated with atypical expression of human neutrophil antigen-2.Semantic proximity Read ↗

Allelic Discrimination by TaqMan-PCR for Genotyping of Human Neutrophil Antigens.Semantic proximity Read ↗

Human Neutrophil Antigen Genotype and Allele Frequencies in Iranian Blood Donors.Semantic proximity Read ↗

Genotyping of human neutrophil antigens by polymerase chain reaction sequence-based typing.Semantic proximity Read ↗

Human neutrophil alloantigens systems.Semantic proximity Read ↗

A sequence-specific polymerase chain reaction method for HNA-2 genotyping: homozygous c.843A>T mutation predicts the absence of CD177.Semantic proximity Read ↗

Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion.Semantic proximity Read ↗

Neutrophil alloantigens.Semantic proximity Read ↗

Flow-Cytometric Analysis of HNA-2 Expression and Phenotypes Among Thai Blood Donors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.