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Article

Molecular basis of NB1 (HNA-2a, CD177) deficiency.

Blood - 1 Jun 2002

Kissel Karin, Scheffler Steffi, Kerowgan Mohammed, Bux Jürgen

Abstract excerpt

Alloimmunization to the neutrophil antigen NB1 (HNA-2a, CD177) can result in immune neutropenia and transfusion-related acute lung injury. Recently, we were able to elucidate the primary structure of NB1. To shed light also on the molecular basis of the NB1-negative phenotype, we studied the neutrophils of 2 women with NB1-specific alloantibodies for intracellular and extracellular NB1 expression, NB1-specific...

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Source

Identifiers

PMID: 12010833
DOI: 10.1182/blood.v99.11.4231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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