Article
Pathology of cavernous malformations.
Handbook of clinical neurology - 1 Jan 2017
Cox Efrem M, Bambakidis Nicholas C, Cohen Mark L
Abstract excerpt
Cavernous malformations (CMs) are low-pressure angiographically occult lesions, composed of blood-filled sinusoidal locules known as "caverns." Although these lesions were once believed to be congenital in nature, there is compelling evidence to support de novo formation of CMs as well. They can occur as sporadic lesions or be inherited in an autosomal-dominant phenotype in familial forms of the disease. The...
Topics
- Apoptosis Regulatory Proteins
- Carrier Proteins
- Endothelial Cells
- Hemangioma, Cavernous, Central Nervous System
- Humans
- Intracranial Arteriovenous Malformations
- KRIT1 Protein
- Membrane Proteins
- Microscopy, Electron, Scanning
- Phenotype
- Proto-Oncogene Proteins