Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Morris Jill K, Uy Roxanne Adeline Z, Vidoni Eric D, Wilkins Heather M, Archer Ashley E, Thyfault John P, Miles John M, Burns Jeffrey M

Abstract excerpt

Alzheimer's disease (AD) may have heterogeneous pathophysiological underpinnings, with risk factors including apolipoprotein rmvarep4 (APOE4) genotype and insulin resistance. We hypothesized that distinct phenotypes exist within AD. We examined APOE4 and metabolic biomarkers in 338 subjects (n = 213 nondemented (ND), n = 125 AD). We further characterized steady state free fatty acid (FFA) levels in a subset of 45...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Acids

Share to Glucose Clamp Technique

Share to Insulin

Share to Insulin Resistance

Share to Neuropsychological Tests

Share to Statistics, Nonparametric

Source

Open in PubMed Open full text

Identifiers

PMID: 28550261
DOI: 10.3233/JAD-170148
PMCID: PMC5776708

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease.PMID 28550261Read ↗

Genetic mutations of APOEε4 carriers in cardiovascular patients lead to the development of insulin resistance and risk of Alzheimer's disease.Semantic proximity Read ↗

APOE genotype and biological age impact inter-omic associations related to bioenergetics.Semantic proximity Read ↗

Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function.Semantic proximity Read ↗

Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome.Semantic proximity Read ↗

Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer's Disease Across Distinct Brain Regions.Semantic proximity Read ↗

The Alzheimer’s Disease Metabolome: Effects of Sex and <i>APOE</i> ε4 genotypeSemantic proximity Read ↗

APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health.Semantic proximity Read ↗

Metabolomics study to identify plasma biomarkers in alzheimer disease: ApoE genotype effect.Semantic proximity Read ↗

<i>APOE</i> Genotype and Biological Age Impact Inter-Omic Associations Related to BioenergeticsSemantic proximity Read ↗

The effect of APOE genotype on Alzheimer's disease risk is influenced by sex and docosahexaenoic acid status.Semantic proximity Read ↗

Bioenergetic and inflammatory systemic phenotypes in Alzheimer's disease APOE ε4-carriers.Semantic proximity Read ↗

Metabolic syndrome marks early risk for cognitive decline with APOE4 gene variation: A case study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.