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Article

Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET.

Nature communications - 26 May 2017

Chen Yang, Zhang Lei, Graf Laura, Yu Bing, Liu Yue, Kochs Georg, Zhao Yongfang, Gao Song

Abstract excerpt

Human myxovirus resistance protein 1 (MxA) restricts a wide range of viruses and is closely related to the membrane-remodelling GTPase dynamin. The functions of MxA rely on domain rearrangements coupled with GTP hydrolysis cycles. To gain insight into this process, we studied real-time domain dynamics of MxA by single-molecule fluorescence resonance energy transfer. We find that the GTPase...

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PMID: 28548099
DOI: 10.1038/ncomms15744
PMCID: PMC5458555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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