Article

The antiviral GTPase MxB is packaged into virions and binds via its N-terminal domain to alphaherpesvirus capsids

2025-08-27

Abstract excerpt

<h4>ABSTRACT</h4> The interferon-inducible myxovirus resistance proteins belong to the dynamin-like GTPases, with MxA being a restriction factor against several RNA viruses, while MxB restricts infections of lentiviruses and herpesviruses. Humans express MxA(1-662) with an N-terminal domain (NTD) of 43 residues, MxB(1-715) with an NTD of 91 residues, and a truncated MxB(26-715) with an NTD of 66 residues. Althoug...

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Literature Corpus work: 07e33693-96d3-5069-907c-b885261e2f43
DOI: 10.1101/2025.08.27.672568

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