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Article

Crystal structure of the GTPase domain of rat dynamin 1.

Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2005

Reubold Thomas F, Eschenburg Susanne, Becker Andreas, Leonard Marilyn, Schmid Sandra L, Vallee Richard B, Kull F Jon, Manstein Dietmar J

Abstract excerpt

Here, we present the 1.9-A crystal structure of the nucleotide-free GTPase domain of dynamin 1 from Rattus norvegicus. The structure corresponds to an extended form of the canonical GTPase fold observed in Ras proteins. Both nucleotide-binding switch motifs are well resolved, adopting conformations that closely resemble a GTP-bound state not previously observed for nucleotide-free GTPases. Two highly conserved...

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Identifiers

PMID: 16141317
DOI: 10.1073/pnas.0506491102
PMCID: PMC1201622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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