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Article

Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell lines.

PloS one - 1 Jan 2017

Noguchi Ken, Dalton Annamarie C, Howley Breege V, McCall Buckley J, Yoshida Akihiro, Diehl J Alan, Howe Philip H

Abstract excerpt

ILEI (FAM3C) is a secreted factor that contributes to the epithelial-to-mesenchymal transition (EMT), a cell biological process that confers metastatic properties to a tumor cell. Initially, we found that ILEI mRNA is highly expressed in melanoma metastases but not in primary tumors, suggesting that ILEI contributes to the malignant properties of melanoma. While melanoma is not an epithelial cell-derived tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28545079
DOI: 10.1371/journal.pone.0177830
PMCID: PMC5435346

Genes

MITF
BDNF
JUN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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