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The FAM3C locus that encodes interleukin-like EMT inducer (ILEI) is frequently co-amplified in MET-amplified cancers and contributes to invasiveness

2021-01-27

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<title>Abstract</title> <p><bold>Background</bold> Gene amplification of <italic>MET</italic>, which encodes for the receptor tyrosine kinase c-MET, occurs in a variety of human cancers. High c-MET levels often correlate with poor cancer prognosis. Interleukin-like EMT inducer (ILEI) is also overexpressed in many cancers and is associated with metastasis and poor survival. The gene for ILEI, <italic>FAM3C</italic...

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Literature Corpus work
debf9e66-b32a-5942-a29a-61cc41c27a85
DOI
10.21203/rs.3.rs-100297/v2
Open publication

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