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Article

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.

The Journal of infectious diseases - 1 Jul 2017

Randolph Adrienne G, Yip Wai-Ki, Allen Emma Kaitlynn, Rosenberger Carrie M, Agan Anna A, Ash Stephanie A, Zhang Yu, Bhangale Tushar R, Finkelstein David, Cvijanovich Natalie Z, Mourani Peter M, Hall Mark W, Su Helen C, Thomas Paul G

Abstract excerpt

Background: Interferon-induced transmembrane protein 3 (IFITM3) restricts endocytic fusion of influenza virus. IFITM3 rs12252_C, a putative alternate splice site, has been associated with influenza severity in adults. IFITM3 has not been evaluated in pediatric influenza. Methods: The Pediatric Influenza (PICFLU) study enrolled children with suspected influenza infection across 38 pediatric intensive care units...

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Source

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Identifiers

PMID: 28531322
DOI: 10.1093/infdis/jix242
PMCID: PMC5853450

Genes

IFITM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.PMID 28531322Read ↗

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