IFITM3 and susceptibility to respiratory viral infections in the community.

doi:10.1093/infdis/jit468

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Article

IFITM3 and susceptibility to respiratory viral infections in the community.

The Journal of infectious diseases - 1 Apr 2014

Mills Tara C, Rautanen Anna, Elliott Katherine S, Parks Tom, Naranbhai Vivek, Ieven Margareta M, Butler Christopher C, Little Paul, Verheij Theo, Garrard Chris S, Hinds Charles, Goossens Herman, Chapman Stephen, Hill Adrian V S

Abstract excerpt

Interferon-inducible transmembrane proteins 1, 2, and 3 (IFITM 1,2, and 3) are viral restriction factors that mediate cellular resistance to several viruses. We have genotyped a possible splice-site altering single-nucleotide polymorphism (rs12252) in the IFITM3 gene in 34 patients with H1N1 influenza and severe pneumonia, and >5000 individuals comprising patients with community-acquired mild lower respiratory...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23997235
DOI: 10.1093/infdis/jit468
PMCID: PMC3952664

Genes

IFITM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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