Article
The Interferon-induced transmembrane protein 3 gene (IFITM3) rs12252 C variant is associated with COVID-19.
Cytokine - 1 Jan 2021
Gómez Juan, Albaiceta Guillermo M, Cuesta-Llavona Elías, García-Clemente Marta, López-Larrea Carlos, Amado-Rodríguez Laura, López-Alonso Inés, Melón Santiago, Alvarez-Argüelles Marta E, Gil-Peña Helena, Vidal-Castiñeira José R, Corte-Iglesias Viviana, Saiz María L, Alvarez Victoria, Coto Eliecer
Abstract excerpt
BACKGROUND AND AIMS: The interferon-induced transmembrane proteins play an important antiviral role by preventing viruses from traversing the cellular lipid bilayer. IFITM3 gene variants have been associated with the clinical response to influenza and other viruses. Our aim was to determine whether the IFITM3 rs12252 polymorphism was associated with the risk of developing severe symptoms of COVID-19 in our...
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