Article
Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission.
Journal of medical virology - 1 Mar 2018
Carter Tonia C, Hebbring Scott J, Liu Jixia, Mosley Jonathan D, Shaffer Christian M, Ivacic Lynn C, Kopitzke Sarah, Stefanski Elisha L, Strenn Rob, Sundaram Maria E, Meece Jennifer, Brilliant Murray H, Ferdinands Jill M, Belongia Edward A
Abstract excerpt
Host response to influenza is highly variable, suggesting a potential role of host genetic variation. To investigate the host genetics of severe influenza in a targeted fashion, 32 single nucleotide polymorphisms (SNPs) within viral immune response genes were evaluated for association with seasonal influenza hospitalization in an adult study population with European ancestry. SNP allele and genotype frequencies...
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