Article
Interpreting findings from Mendelian randomization using the MR-Egger method.
European journal of epidemiology - 1 May 2017
Burgess Stephen, Thompson Simon G
Abstract excerpt
Mendelian randomization-Egger (MR-Egger) is an analysis method for Mendelian randomization using summarized genetic data. MR-Egger consists of three parts: (1) a test for directional pleiotropy, (2) a test for a causal effect, and (3) an estimate of the causal effect. While conventional analysis methods for Mendelian randomization assume that all genetic variants satisfy the instrumental variable assumptions, the...
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