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Article

Quantitative specificity of STAT1 and several variants.

Nucleic acids research - 21 Aug 2017

Roy Basab, Zuo Zheng, Stormo Gary D

Abstract excerpt

The quantitative specificity of the STAT1 transcription factor was determined by measuring the relative affinity to hundreds of variants of the consensus binding site including variations in the length of the site. The known consensus sequence is observed to have the highest affinity, with all variants decreasing binding affinity considerably. There is very little loss of binding affinity when the CpG within the...

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Share to CpG Islands
Share to DNA Methylation
Share to Binding, Competitive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Electrophoresis, Polyacrylamide Gel

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Source

Open in PubMed Open full text

Identifiers

PMID: 28510715
DOI: 10.1093/nar/gkx393
PMCID: PMC5737217

Genes

STAT1
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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