Article
Naturally occurring dominant negative variants of Stat5.
Molecular and cellular biology - 1 Nov 1996
Wang D, Stravopodis D, Teglund S, Kitazawa J, Ihle J N
Abstract excerpt
Stat5 was initially identified as a prolactin-induced member of the signal transducer and activator of transcription (Stat) family in sheep. However, Stat5 is also activated in the response to a variety of cytokines. In mice, and possibly in other species, there exist two Stat5 genes (Stat5a and Stat5b) that encode proteins of 92 and 94 kDa that are 95% identical. In the studies described here, we demonstrate...
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