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Article

Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.

Molecular and cellular biology - 1 Aug 2008

Thomas Tim, Dixon Mathew P, Kueh Andrew J, Voss Anne K

Abstract excerpt

Acetylation of histone tails is a hallmark of transcriptionally active chromatin. Mof (males absent on the first; also called MYST1 or KAT8) is a member of the MYST family of histone acetyltransferases and was originally discovered as an essential component of the X chromosome dosage compensation system in Drosophila. In order to examine the role of Mof in mammals in vivo, we generated mice carrying a null...

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Source

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Identifiers

PMID: 18541669
DOI: 10.1128/MCB.02202-07
PMCID: PMC2519697

Genes

KAT8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.PMID 18541669Read ↗

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