Article
Polymorphic variants of genes involved in choline pathway and the risk of intrauterine fetal death.
Ginekologia polska - 1 Jan 2017
Drews Krzysztof, Różycka Agata, Barlik Magdalena, Klejewski Andrzej, Kurzawińska Grażyna, Wolski Hubert, Majchrzycki Marian, Gryszczyńska Agnieszka, Kamiński Adam, Seremak-Mrozikiewicz Agnieszka
Abstract excerpt
OBJECTIVES: Choline and folate metabolism disturbances may be involved in the occurrence of intrauterine fetal death (IUFD). The proper activity of this metabolism could be determined by genetic variants involved in choline pathway e.g. CHKA (gene encoding choline kinase α), PCYT1A (gene encoding CCTα) and CHDH (gene encoding choline dehydrogenase). Our study aimed at determining the genotype and allele...
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