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Article

Polymorphic variants of folate and choline metabolism genes and the risk of endometriosis-associated infertility.

European journal of obstetrics, gynecology, and reproductive biology - 1 Jul 2011

Szczepańska Malgorzata, Mostowska Adrianna, Wirstlein Przemyslaw, Lianeri Margarita, Marianowski Piotr, Skrzypczak Jana, Jagodziński Paweł P

Abstract excerpt

OBJECTIVE: Endometriosis has been considered an epigenetic disease. Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity. STUDY DESIGN: We studied 16 SNPs in 12 folate and choline metabolism genes, including BHMT (rs7356530 and rs3733890), BHMT2 (rs625879), CBS (844ins68), CHDH (rs893363 and rs2289205), CHKA...

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Share to Choline
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Share to Infertility, Female
Share to Methylenetetrahydrofolate Reductase (NADPH2)
Share to Multifactor Dimensionality Reduction
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Source

Identifiers

PMID: 21429654
DOI: 10.1016/j.ejogrb.2011.02.003

Genes

CBS
MTHFR
MTR
PEMT
BHMT
BHMT2
CHDH
CHKA
MTHFD1
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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