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Article

The chromokinesin Klp3a and microtubules facilitate acentric chromosome segregation.

The Journal of cell biology - 5 Jun 2017

Karg Travis, Elting Mary Williard, Vicars Hannah, Dumont Sophie, Sullivan William

Abstract excerpt

Although poleward segregation of acentric chromosomes is well documented, the underlying mechanisms remain poorly understood. Here, we demonstrate that microtubules play a key role in poleward movement of acentric chromosome fragments generated in Drosophila melanogaster neuroblasts. Acentrics segregate with either telomeres leading or lagging in equal frequency and are preferentially associated with peripheral...

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Identifiers

PMID: 28500183
DOI: 10.1083/jcb.201604079
PMCID: PMC5461011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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