Article
Characterization of KCNE1 inside Lipodisq Nanoparticles for EPR Spectroscopic Studies of Membrane Proteins.
The journal of physical chemistry. B - 1 Jun 2017
Sahu Indra D, Zhang Rongfu, Dunagan Megan M, Craig Andrew F, Lorigan Gary A
Abstract excerpt
EPR spectroscopic studies of membrane proteins in a physiologically relevant native membrane-bound state are extremely challenging due to the complexity observed in inhomogeneity sample preparation and dynamic motion of the spin-label. Traditionally, detergent micelles are the most widely used membrane mimetics for membrane proteins due to their smaller size and homogeneity, providing high-resolution structure...
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