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Article

Self-assembling study of sarcolipin and its mutants in multiple molecular dynamic simulations.

Proteins - 1 Jun 2017

Cao Yipeng, Wu Xue, Yang Rui, Wang Xinyu, Sun Haiying, Lee Imshik

Abstract excerpt

The Sarcolipin (SLN) is a single trans-membrane protein that can self-assembly to dimer and oligomer for playing importantphysiological function. In this work, we addressed the dimerization of wild type SLN (wSLN) and its mutants (mSLNs) - I17A and I20A, using both coarse-grained (CG) and atomistic (AT) molecular dynamics (MD) simulations. Our results demonstrated that wSLN homodimer assembled as a left-handed...

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Source

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PMID: 28241400
DOI: 10.1002/prot.25273

Genes

SLN

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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