Article

Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types

2023-11-10

Abstract excerpt

Aquaporin-1 (Aqp1), a water channel, has garnered significant interest for cell-based medicine and in vivo synthetic biology due to its ability to be genetically encoded to produce magnetic resonance signals by increasing the rate of water diffusion in cells. However, concerns regarding the effects of Aqp1 overexpression and increased membrane diffusivity on cell physiology have limited its widespread use as a dee...

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Identifiers and source

Literature Corpus work: 531c612c-2922-5b99-a945-906cb34f97dd
DOI: 10.1101/2023.11.07.566095

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