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Article

Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals.

Translational psychiatry - 9 May 2017

Gross J A, Pacis A, Chen G G, Drupals M, Lutz P-E, Barreiro L B, Turecki G

Abstract excerpt

5-Hydroxymethylcytosine (5hmC) is a recently characterized epigenetic mark that is particularly abundant in brain tissue and that regulates gene transcription. We have recently begun to understand the important role of 5hmC in brain development, plasticity and disease, but there are currently little data on 5hmC alterations in psychiatric illnesses. Here we report what we believe to be the first genome-wide...

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Identifiers

PMID: 28485726
DOI: 10.1038/tp.2017.93
PMCID: PMC5534961

Genes

MYO16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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