Article
Increased susceptibility for aspergillosis and post-transplant immune deficiency in patients with gene variants of TLR4 after stem cell transplantation.
Transplant infectious disease : an official journal of the Transplantation Society - 1 Oct 2013
Koldehoff M, Beelen D W, Elmaagacli A H
Abstract excerpt
INTRODUCTION: Toll-like receptors (TLRs) detect invading pathogens through several pattern-recognition mechanisms and play a central role in the regulation of the immune system. In allogeneic hematopoietic stem cell transplantation (HSCT), the frequent opportunistic fungal infections remain an important cause of mortality and morbidity in these highly immunocompromised patients. METHODS: We analyzed 154 patients...
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