Article
The Leu72Met Polymorphism of the Prepro-ghrelin Gene is Associated With Alcohol Consumption and Subjective Responses to Alcohol: Preliminary Findings.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jul 2017
Suchankova Petra, Yan Jia, Schwandt Melanie L, Stangl Bethany L, Jerlhag Elisabet, Engel Jörgen A, Hodgkinson Colin A, Ramchandani Vijay A, Leggio Lorenzo
Abstract excerpt
AIMS: The orexigenic peptide ghrelin may enhance the incentive value of food-, drug- and alcohol-related rewards. Consistent with preclinical findings, human studies indicate a role of ghrelin in alcohol use disorders (AUD). In the present study an a priori hypothesis-driven analysis was conducted to investigate whether a Leu72Met missense polymorphism (rs696217) in the prepro-ghrelin gene (GHRL), is associated...
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