Article
A case control study investigating the methylation levels of GHRL and GHSR genes in alcohol use disorder.
Molecular biology reports - 21 May 2024
Özkan-Kotiloğlu Selin, Kaya-Akyüzlü Dilek, Güven Emine, Doğan Özlem, Ağtaş-Ertan Ece, Özgür-İlhan İnci
Abstract excerpt
BACKGROUND: Alcohol use disorder (AUD) is a relapsing disease described as excessive use of alcohol. Evidence of the role of DNA methylation in addiction is accumulating. Ghrelin is an important peptide known as appetite hormone and its role in addictive behavior has been identified. Here we aimed to determine the methylation levels of two crucial genes (GHRL and GHSR) in ghrelin signaling and further investigate...
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