Article
Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2006
Ando Tetsuya, Komaki Gen, Naruo Tetsuro, Okabe Kenjiro, Takii Masato, Kawai Keisuke, Konjiki Fujiko, Takei Michiko, Oka Takakazu, Takeuchi Kaori, Masuda Akinori, Ozaki Norio, Suematsu Hiroyuki, Denda Kenzo, Kurokawa Nobuo, Itakura Kotarou, Yamaguchi Chikara, Kono Masaki, Suzuki Tatsuyo, Nakai Yoshikatsu, Nishizono-Maher Aya, Koide Masanori, Murakami Ken, Nagamine Kiyohide, Tomita Yuichiro, Ookuma Kazuyoshi, Tomita Kazumi, Tonai Eita, Ooshima Akira, Ishikawa Toshio, Ichimaru Yuhei
Abstract excerpt
Previous investigations have suggested that ghrelin, an endogenous orexigenic peptide, is involved in the pathology of eating disorders. We conducted a study to determine whether any preproghrelin gene polymorphisms are associated with eating disorders. Three hundred thirty-six eating disorder patients, including 131 anorexia nervosa (AN)-restricting types (AN-R), 97 AN-binge eating/purging types (AN-BP) and 108...
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