Article
Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.
Alcoholism, clinical and experimental research - 1 Dec 2008
Landgren Sara, Jerlhag Elisabet, Zetterberg Henrik, Gonzalez-Quintela Arturo, Campos Joaquin, Olofsson Ulrica, Nilsson Staffan, Blennow Kaj, Engel Jörgen A
Abstract excerpt
BACKGROUND: Ghrelin, an orexigenic peptide, acts on growth hormone secretagogue receptors (GHS-R1A), expressed in the hypothalamus as well as in important reward nodes such as the ventral tegmental area. Interestingly, ghrelin has been found to activate an important part of the reward systems, i....
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