Article
Complete genome sequencing and clinical analysis of intrahepatic hepatitis B virus cccDNA from HCC.
Microbial pathogenesis - 1 Aug 2017
Jiao Fengping, Long Lu, Ding Shanlong, Xie Xiaomeng, Jia Le, Lu Fengmin
Abstract excerpt
BACKGROUND: More than half of hepatocellular carcinomas (HCCs) are etiologically attributed to hepatitis B virus (HBV) infection, but it remains unclear whether HBV mutations are virological factors that contribute to formation of HCC or instead reflect accumulation during the progression of HBV-related disease. METHODS: Rolling-cycle amplification and PCR sequencing were used to characterize covalently closed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.