Article
High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells.
Oncotarget - 18 Jul 2017
Li Hui, Gao Shuai, Huang Hua, Liu Wenqiang, Huang Huanwei, Liu Xiaoyu, Gao Yawei, Le Rongrong, Kou Xiaochen, Zhao Yanhong, Kou Zhaohui, Li Jia, Wang Hong, Zhang Yu, Wang Hailin, Cai Tao, Sun Qingyuan, Gao Shaorong, Han Zhiming
Abstract excerpt
Somatic cell nuclear transfer and transcription factor mediated reprogramming are two widely used techniques for somatic cell reprogramming. Both fully reprogrammed nuclear transfer embryonic stem cells and induced pluripotent stem cells hold potential for regenerative medicine, and evaluation of the stem cell pluripotency state is crucial for these applications. Previous reports have shown that the Dlk1-Dio3...
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