Article

Somatic Cell Nuclear Transfer Embryos Show Massive Dysregulation of Genes Involved in Transcription Pathways

2020-12-07

Abstract excerpt

Transcription is the most fundamental molecular event that occurs with zygotic genome activation (ZGA) during embryo development. However, the potential association between transcription pathways and low cloning efficiency of nuclear transfer (NT) embryos remains elusive. Here, we integrated a series of RNA-seq data on NT embryos to deciphering the molecular barriers of NT embryo development. Comparative transcrip...

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Literature Corpus work: 614445ff-a70b-5b42-89c1-ecf24638001d
DOI: 10.1101/2020.12.06.413393

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