Article
CYP2E1 rs2031920, COMT rs4680 Polymorphisms, Cigarette Smoking, Alcohol Use and Lung Cancer Risk in a Japanese Population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Kakino Kenichi, Kiyohara Chikako, Horiuchi Takahiko, Nakanishi Yoichi
Abstract excerpt
BACKGROUND: Cytochrome P450 2E1 (CYP2E1) and catechol-O-methyltransferase (COMT) genes may contribute to susceptibility to lung cancer because of their critical involvement in mechanisms of carcinogenesis. MATERIALS AND METHODS: We evaluated the role of CYP2E1 rs2031920 and COMT rs4680 in a case-control study involving 462 lung cancer cases and 379 controls in Japanese. Logistic regression was used to assess...
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