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Article

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects.

Investigative ophthalmology & visual science - 1 May 2017

Yoshikawa Munemitsu, Nakanishi Hideo, Yamashiro Kenji, Miyake Masahiro, Akagi Tadamichi, Gotoh Norimoto, Ikeda Hanako O, Suda Kenji, Yamada Hiroshi, Hasegawa Tomoko, Iida Yuto, Yamada Ryo, Matsuda Fumihiko, Yoshimura Nagahisa

Abstract excerpt

Purpose: To examine the associations of the earlier reported glaucoma-related genes to the regional circumpapillary retinal nerve fiber layer thicknesses (cpRNFLTs) and corresponding visual field defects. Methods: We studied 756 patients with primary open-angle glaucoma (POAG) and 3094 normal controls. Each participant was genotyped for nine single nucleotide polymorphisms (SNPs) of four glaucoma-susceptible...

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Source

Identifiers

PMID: 28472212
DOI: 10.1167/iovs.16-20797

Genes

CAV1
CAV2
SIX1
SIX6
TMCO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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