Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study.

doi:10.1167/iovs.14-15863

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Article

Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study.

Investigative ophthalmology & visual science - 23 Dec 2014

Cheng Ching-Yu, Allingham R Rand, Aung Tin, Tham Yih-Chung, Hauser Michael A, Vithana Eranga N, Khor Chiea Chuen, Wong Tien Yin

Abstract excerpt

PURPOSE: Recently the common SIX6 missense variant rs33912345 was found to be highly associated with glaucoma. The aim of this study was to investigate the association between this SIX6 variant and peripapillary retinal nerve fiber layer (RNFL) thickness measured by spectral-domain optical coherence tomography (SD-OCT) in a population setting. METHODS: Study subjects were enrolled from the Singapore Chinese Eye...

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PMID: 25537207
DOI: 10.1167/iovs.14-15863
PMCID: PMC4544593

Genes

SIX6

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