Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glaucoma risk alleles at CDKN2B-AS1 are associated with lower intraocular pressure, normal-tension glaucoma, and advanced glaucoma.

Ophthalmology - 1 Aug 2012

Burdon Kathryn P, Crawford April, Casson Robert J, Hewitt Alex W, Landers John, Danoy Patrick, Mackey David A, Mitchell Paul, Healey Paul R, Craig Jamie E

Abstract excerpt

PURPOSE: Genetic variation at the 9p21 locus encompassing the CDKN2B-AS1, CDKN2A, and CDKN2B genes has been associated with primary open-angle glaucoma (POAG) in several independent studies. This study aimed to dissect the association further and to determine genotype-phenotype correlations between genetic variation at this locus and a range of glaucoma-related traits in a large cohort of POAG patients. DESIGN:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 9
Share to Glaucoma, Open-Angle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intraocular Pressure

Share to Optic Disk

Share to Optic Nerve Diseases

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Tonometry, Ocular

Source

Identifiers

PMID: 22521085
DOI: 10.1016/j.ophtha.2012.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glaucoma risk alleles at CDKN2B-AS1 are associated with lower intraocular pressure, normal-tension glaucoma, and advanced glaucoma.PMID 22521085Read ↗

Genetic Association at the 9p21 Glaucoma Locus Contributes to Sex Bias in Normal-Tension Glaucoma.Semantic proximity Read ↗

Common variants on chromosome 9p21 are associated with normal tension glaucoma.Semantic proximity Read ↗

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.Semantic proximity Read ↗

Genetic association between CDKN2B-AS1 polymorphisms and the susceptibility of primary open-angle glaucoma (POAG): a meta-analysis from 21,775 subjects.Semantic proximity Read ↗

Genetic Variants Associated With Different Risks for High Tension Glaucoma and Normal Tension Glaucoma in a Chinese Population.Semantic proximity Read ↗

Genome-wide multi-ethnic meta-analysis identifies 22 independent risk loci for normal tension glaucoma and predominantly overlaps with high tension glaucoma.Semantic proximity Read ↗

An Updated Review on the Genetics of Primary Open Angle Glaucoma.Semantic proximity Read ↗

Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese.Semantic proximity Read ↗

Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis.Semantic proximity Read ↗

CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States.Semantic proximity Read ↗

DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma.Semantic proximity Read ↗

Common genetic variants associated with open-angle glaucoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.