Article
Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.
Ophthalmology - 1 Feb 2014
Loomis Stephanie J, Kang Jae H, Weinreb Robert N, Yaspan Brian L, Cooke Bailey Jessica N, Gaasterland Douglas, Gaasterland Terry, Lee Richard K, Lichter Paul R, Budenz Donald L, Liu Yutao, Realini Tony, Friedman David S, McCarty Catherine A, Moroi Sayoko E, Olson Lana, Schuman Joel S, Singh Kuldev, Vollrath Douglas, Wollstein Gadi, Zack Donald J, Brilliant Murray, Sit Arthur J, Christen William G, Fingert John, Kraft Peter, Zhang Kang, Allingham R Rand, Pericak-Vance Margaret A, Richards Julia E, Hauser Michael A, Haines Jonathan L, Pasquale Louis R, Wiggs Janey L
Abstract excerpt
PURPOSE: The CAV1/CAV2 (caveolin 1 and caveolin 2) genomic region previously was associated with primary open-angle glaucoma (POAG), although replication among independent studies has been variable. The aim of this study was to assess the association between CAV1/CAV2 single nucleotide polymorphisms (SNPs) and POAG in a large case-control dataset and to explore associations by gender and pattern of visual field...
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