Article
Interacting motif networks located in hotspots associated with RNA release are conserved in Enterovirus capsids.
FEBS letters - 1 Jun 2017
Ross Caroline, Knox Caroline, Tastan Bishop Özlem
Abstract excerpt
Enteroviruses are responsible for a multitude of human diseases. Expansion of the virus capsid is associated with a cascade of conformational changes that allow the subsequent release of RNA. For the first time, this study presents a comprehensive bioinformatic screen for the prediction of interacting motifs within intraprotomer interfaces and across respective interfaces surrounding the fivefold and twofold...
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