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Article

Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades.

Journal of virology - 15 Jul 2017

Sharma Sumit, Carlsson Beatrice, Czakó Rita, Vene Sirkka, Haglund Mats, Ludvigsson Johnny, Larson Göran, Hammarström Lennart, Sosnovtsev Stanislav V, Atmar Robert L, Green Kim Y, Estes Mary K, Svensson Lennart

Abstract excerpt

The emergence of pandemic GII.4 norovirus (NoV) strains has been proposed to occur due to changes in receptor usage and thereby to lead to immune evasion. To address this hypothesis, we measured the ability of human sera collected between 1979 and 2010 to block glycan binding of four pandemic GII.4 noroviruses isolated in the last 4 decades. In total, 268 sera were investigated for 50% blocking titer (BT50)...

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Identifiers

PMID: 28468886
DOI: 10.1128/JVI.00567-17
PMCID: PMC5487561

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FUT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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